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Publications
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis,10.1101/gad.1549407,Genes & Development,B. Ancrile,K.-H. Lim,C. M. Counter
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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
(
Citations: 53
)
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B. Ancrile
,
K.-H. Lim
,
C. M. Counter
Journal:
Genes & Development - GENE DEVELOP
, vol. 21, no. 14, pp. 1714-1719, 2007
DOI:
10.1101/gad.1549407
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The following links allow you to view full publications. These links are maintained by other sources not affiliated with Microsoft Academic Search.
(
www.genesdev.org
)
Citation Context
(12)
...,
...
Hee Ja Kim
,
et al.
Loss of the Promyelocytic Leukemia Protein in Gastric Cancer: Implicat...
...© 2011 BioMed Central Ltd IL-6 even in monolayer cultures [
8
]...
Senthil K Muthuswamy
.
3D culture reveals a signaling network
...20 is a downstream effector of oncogenic
ras
...
F Balkwill
,
et al.
Cancer and Inflammation: Implications for Pharmacology and Therapeutic...
...Knockdown of IL-6, genetic ablation of IL-6, or treatment with a neutralizing IL-6 antibody can thwart Ras-mediated tumorigenesis [
119
]...
Gaoliang Ouyang
,
et al.
Molecular signaling of the epithelial to mesenchymal transition in gen...
...pSuper IL-6 shRNA was a gift from C. Counter [
23
]...
...Furthermore, it was shown that a number of Ras transformed cells express high levels of IL-6 which promotes angiogenesis and tumorigenesis [
23
]...
...IL-6 was shown to be expressed to high levels in numerous Ras-expressing cell lines including kidney, fibroblasts, human mammary epithelial cells and pancreatic cancer derived cell lines when grown in 2-D [
23
]...
...A requirement for IL-6 signaling in tumor formation has been demonstrated by using IL-6 knock-down approaches as well as blocking antibodies to IL-6 in a variety of cell types [
23
,32,70,71]...
Kenneth Leslie
,
et al.
Differential interleukin-6/Stat3 signaling as a function of cellular c...
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Citations
(53)
Loss of the Promyelocytic Leukemia Protein in Gastric Cancer: Implications for IP10 Expression and Tumor-Infiltrating Lymphocytes
Hee Ja Kim
,
Dong Eun Song
,
Seul Ye Lim
,
Sung-Hee Lee
,
Jihee Lee Kang
,
Sun Jung Lee
,
Etty N. Benveniste
,
Youn-Hee Choi
,
Yoshio Yamaoka
Journal:
PLOS One
, vol. 6, no. 10, 2011
3D culture reveals a signaling network
Senthil K Muthuswamy
Journal:
Breast Cancer Research - BREAST CANCER RES
, vol. 13, no. 1, pp. 1-2, 2011
Cancer and Inflammation: Implications for Pharmacology and Therapeutics
(
Citations: 28
)
F Balkwill
,
A Mantovani
Journal:
Clinical Pharmacology & Therapeutics - CLIN PHARMACOL THER
, vol. 87, no. 4, pp. 401-406, 2010
Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways
(
Citations: 21
)
Aaron J. Schetter
,
Niels H. H. Heegaard
,
Curtis C. Harris
Published in 2010.
Inflammation and oncogenesis: a vicious connection
(
Citations: 14
)
Sergei I Grivennikov
,
Michael Karin
Journal:
Current Opinion in Genetics & Development - CURR OPIN GENET DEVELOP
, vol. 20, no. 1, pp. 65-71, 2010